ATG10 Antikörper (C-Term)

Produktnummer ABIN2785625

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch ATG10 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen und Pferd.

Kurzübersicht für ATG10 Antikörper (C-Term) (ABIN2785625)

Target: ATG10 (Autophagy Related 10 (ATG10))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ATG10 Antikörper

Bindungsspezifität: C-Term

Sequenz: TPVLKNSQKI NKNVNYITSW LSIVGPVVGL NLPLSYAKAT SQDERNVP

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ATG10. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ATG10

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 220 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ATG10

Target: ATG10 (Autophagy Related 10 (ATG10))

Andere Bezeichnung: ATG10

Hintergrund: Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A), a homolog of yeast Apg8, to a membrane-bound form.Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A, MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM].
Alias Symbols: APG10, APG10L, DKFZP586I0418, FLJ13954, pp12616
Protein Interaction Partner: ATG3, ATG4B, ATG7, HAT1, USP11, USP7, RBBP7, MAP1B, KRT85, ADSS, ATG5, ATG12,
Protein Size: 220

Molekulargewicht: 25 kDa

Gen-ID: 83734

NCBI Accession: NM_031482, NP_113670

UniProt: Q9H0Y0

Pathways: ER-Nucleus Signaling, Autophagie